What potential problem could arise from the pacing with a unipolar lead?

Pacing with a unipolar lead can potentially result in pacing inhibition due to interference. This issue arises from the nature of unipolar pacing which involves a single lead that generates a pacing impulse to the heart, with the return pathway being through the skin to an indifferent electrode. Because of this configuration, unipolar pacing can pick up electrical noise or artifacts from various sources, such as muscle movements or other electrical devices nearby. This interference can disrupt the pacing signal, leading the device to incorrectly interpret the interference as a natural heartbeat. As a consequence, the device may inhibit pacing when it shouldn't, which can ultimately compromise the intended pacing therapy and the patient's heart rhythm stability. This characteristic highlights the importance of understanding the technical implications of lead selection in cardiac pacing procedures.